Mass Spectrometer GC-MS-QP-2010

Gas Chromatography and Mass spectrometry combines two powerful techniques to provide the identification of compounds with low detection limits and the potential for quantitative analysis
Liquid, gaseous and solid samples work well with GC-MS analysis. However, analyzed compounds are typically volatile and semi-volatile
In Gas Chromatography (GC), a sample is volatilized and carried by an inert gas through a coated glass capillary column. The “stationary phase” is bonded to the interior of the column. Retention time is how long that a compound takes a pass through the column to the detector. Finally, the sample is identified by comparing the sample with a reference
In the usual Mass spectrometry step of GC-MS, compounds leaving the GC column are fragmented by electron impact. The charged fragments are detected and the subsequent spectrum obtained can be used to identify the molecule Fragmentation patterns are reproducible and can be used to produce quantitative measurements.

GC-MS analysis of liquids, gases and solids
Gas Chromatography Mass Spectrometry analyses are performed on liquids, gases or solids. For liquids and gases, the sample is commonly directly injected the GC. For solids, the analysis is carried out by solvent extraction, outgassing(desorption) or pyrolysis